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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MAP4K5 All Species: 26.97
Human Site: T178 Identified Species: 53.94
UniProt: Q9Y4K4 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y4K4 NP_006566.2 846 95040 T178 K R K S F I G T P Y W M A P E
Chimpanzee Pan troglodytes XP_001155473 846 95023 T178 K R K S F I G T P Y W M A P E
Rhesus Macaque Macaca mulatta A4K2T0 487 55587
Dog Lupus familis XP_851371 846 95039 T178 K R K S F I G T P Y W M A P E
Cat Felis silvestris
Mouse Mus musculus Q8BPM2 847 95026 T178 K R K S F I G T P Y W M A P E
Rat Rattus norvegicus Q924I2 873 98660 T174 K R K S F I G T P Y W M A P E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515144 898 100018 T230 K R K S F I G T P Y W M A P E
Chicken Gallus gallus Q5ZJK4 486 55318
Frog Xenopus laevis Q6IP06 493 56486
Zebra Danio Brachydanio rerio Q7ZUQ3 492 56062
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8T0S6 669 75091 M45 P E K V F D I M Y K L G E G S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q23356 1096 122486 T189 R R N T F I G T P Y W M A P E
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 25.2 98.1 N.A. 95.9 68.7 N.A. 87 24.5 25.4 25 N.A. 25.8 N.A. 23.8 N.A.
Protein Similarity: 100 99.7 39.8 99 N.A. 98.2 81.3 N.A. 90 39.7 40.3 40.5 N.A. 43.2 N.A. 41 N.A.
P-Site Identity: 100 100 0 100 N.A. 100 100 N.A. 100 0 0 0 N.A. 13.3 N.A. 80 N.A.
P-Site Similarity: 100 100 0 100 N.A. 100 100 N.A. 100 0 0 0 N.A. 13.3 N.A. 93.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 59 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 9 0 0 0 0 0 0 0 0 0 0 9 0 59 % E
% Phe: 0 0 0 0 67 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 59 0 0 0 0 9 0 9 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 59 9 0 0 0 0 0 0 0 0 % I
% Lys: 50 0 59 0 0 0 0 0 0 9 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 9 0 0 0 59 0 0 0 % M
% Asn: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 9 0 0 0 0 0 0 0 59 0 0 0 0 59 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 9 59 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 50 0 0 0 0 0 0 0 0 0 0 9 % S
% Thr: 0 0 0 9 0 0 0 59 0 0 0 0 0 0 0 % T
% Val: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 59 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 9 59 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _